Vitamin K Deficiency Bleeding (VKDB) of the Newborn (2024)

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What is vitamin K deficiency bleeding in a newborn?

Vitamin K deficiency bleeding (VKDB) is a problem that occurs insome newborn babies. It most often happens during the first few days and weeks of life. But it can occur up to 6 months of age. This condition used to be called hemorrhagic disease of the newborn.

What causes vitamin K deficiency bleeding in a newborn?

Babies are born with low levels of vitamin K. Vitamin K is needed for blood to clot. Not having enough vitamin K is the main cause of vitamin deficiency bleeding. If your baby’s blood doesn’t clot, they may have severe bleeding or a hemorrhage. This can be life-threatening. The cause of vitamin K deficiency depends on the 3 types of VKDB:

  • Early VKDB. This can occur right after birth or up to 24 hours of age. It's caused by certain medicines that a person may take during pregnancy

  • Classical VKDB. This occurs from 1 to 7 days after birth. It's caused by low levels of vitamin K found in newborns.

  • Late VKDB. This most often occurs up to 3 months after birth. But it can occur up to 6 months after birth. It can occur in a baby who did not get a vitamin K shot at birth and who was breastfed.

Which newborns are at risk for vitamin K deficiency bleeding?

These things may make it more likely for a baby to have this condition:

  • Not getting a vitamin K shot at birth. The American Academy of Pediatrics recommends that all newborns get a vitamin K shot. This can prevent severe bleeding.

  • Being breastfed only and not getting a vitamin K shot at birth. Human milk has less vitamin K than formula. Formula is made with cow’s milk and has added vitamin K. The vitamin K shot will provide what a breastfed baby needs. A birth parent who takes a vitamin K supplement while breastfeeding will not raise their baby's vitamin K level.

  • Being born to a parent who took certain medicines during pregnancy. These include medicines for seizures (anticonvulsants) and medicines for blood-clotting problems (anticoagulants).

What are the symptoms of vitamin K deficiency bleeding in a newborn?

Symptoms can be different in each child. They can include:

  • Blood in your baby's stool that make it black and sticky (tarry)

  • Blood in your baby's urine

  • Oozing of blood from around your baby’s umbilical cord or circumcision site

  • Bruising more easily than normal. This may happen around your baby's head and face.

  • Being very sleepy or fussy. In severe cases, vitamin K deficiency may cause bleeding in and around the brain. Other signs of bleeding in the brain can include seizures or vomiting, not just spitting up.

The symptoms of this condition may be similar to symptoms of other health issues. Make sure your child sees a healthcare provider for a diagnosis.

How is vitamin K deficiency bleeding in a newborn diagnosed?

The healthcare provider will look at your baby's health history and check your baby for signs of bleeding. Your baby may need lab tests to measure their blood clotting times. The results of these tests can help your child’s healthcare provider make the diagnosis.

How is vitamin K deficiency bleeding in a newborn treated?

Treatment will depend on your child’s symptoms, age, and general health. It will also depend on how severe the condition is.

Your baby will probably get a vitamin K shot.

Your baby may need a blood transfusion if they have severe bleeding. If your baby is severely ill, they may need to be treated in the intensive care unit.

What are possible complications of vitamin K deficiency bleeding in a newborn?

Vitamin K deficiency bleeding can lead to life-threatening problems. These include dangerous bleeding that can lead to brain damage or death. In the U.S., deaths and long-term complications from vitamin K deficiency have been greatly lowered because of vitamin K shots given at birth. But bleeding into the brain, central nervous system, stomach, intestines, or other parts of the body can cause serious problems, or even death.

Can vitamin K deficiency bleeding in a newborn be prevented?

This condition can be prevented. The American Academy of Pediatrics recommends that all newborns get a vitamin K shot. Your child will get a shot in their upper leg (thigh) muscle. This shot will be given soon after birth. This will prevent dangerous bleeding.

Key points about vitamin K deficiency bleeding in a newborn

  • Vitamin K deficiency bleeding is a problem that occurs insome newborns. It often happens during the first few days of life but may happen in the first few months

  • Babies are normally born with low levels of vitamin K. Not having enough vitamin K is the main cause of this condition.

  • Your child’s healthcare provider will diagnose this condition. This will be based on your child’s signs of bleeding and lab tests for blood clotting times.

  • The American Academy of Pediatrics recommends that all newborns get a vitamin K shot. This can prevent this condition.

Next steps

Tips to help you get the most from a visit to your child’s healthcare provider:

  • Know the reason for the visit and what you want to happen.

  • Before your visit, write down questions you want answered.

  • At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new directions your provider gives you for your child.

  • Know why a new medicine or treatment is prescribed and how it will help your child. Also know what the side effects are.

  • Ask if your child’s condition can be treated in other ways.

  • Know why a test or procedure is recommended and what the results could mean.

  • Know what to expect if your child does not take the medicine or have the test or procedure.

  • If your child has a follow-up appointment, write down the date, time, and purpose for that visit.

  • Know how you can contact your child’s healthcare provider after office hours, and on weekends and holidays. This is important if your child becomes ill and you have questions or need advice.

Online Medical Reviewer:Donna Freeborn PhD CNM FNP
Online Medical Reviewer:Kimberly Lee MD
Online Medical Reviewer:Stacey Wojcik MBA BSN RN

Date Last Reviewed:9/1/2023

© 2000-2024 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

Vitamin K Deficiency Bleeding (VKDB) of the Newborn (2024)

FAQs

Vitamin K Deficiency Bleeding (VKDB) of the Newborn? ›

Vitamin K deficiency bleeding, or VKDB, occurs when babies cannot stop bleeding because their blood does not have enough vitamin K to form a clot.

Can vitamin K deficiency cause bleeding in newborns? ›

Vitamin K deficiency is a condition that causes newborn babies to bleed uncontrollably because they don't have enough vitamin K to clot their blood. Newborns don't receive a lot of vitamin K through the placenta or their liver. Their gut can't make enough.

What is the complication of VKDB? ›

Late VKDB: This most commonly presents as intracranial, cutaneous, or gastrointestinal bleeding. Intracranial hemorrhage may cause seizures, altered sensorium, and death.

What are four signs of deficiency of vitamin K? ›

Vitamin K deficiency symptoms
  • bruises easily.
  • gets small blood clots underneath their nails.
  • bleeds in mucous membranes that line areas inside the body.
  • produces stool that looks dark black (almost like tar) and contains some blood.
Jun 21, 2017

How do you treat VKDB? ›

Specific treatment for VKDB will be determined by your baby's doctor. The American Academy of Pediatrics recommends giving every newborn baby an injection of vitamin K after delivery, as well as supplementing feedings with infant formulas that contain vitamin K, to prevent this potentially life-threatening disease.

How common is VKDB? ›

Early and classical VKDB are more common, occurring in 1 in 60 to 1 in 250 newborns, although the risk is much higher for early VKDB among those infants whose mothers used certain medications during the pregnancy. Late VKDB is rarer, occurring in 1 in 14,000 to 1 in 25,000 infants(13).

How do you treat vitamin K deficiency bleeding? ›

For adults, the preferred method of maintaining adequate vitamin K levels and treating minor bleeding is through oral vitamin K supplementation or occasional subcutaneous injection. IV administration is typically reserved for cases of severe bleeding.

What causes bleeding in newborns? ›

Hemorrhagic disease is a bleeding problem that occurs in a baby during the first few days of life. Babies are normally born with low levels of vitamin K, an essential factor in blood clotting. A deficiency in vitamin K is the main cause of hemorrhagic disease in newborn babies.

Why are babies born with low levels of vitamin K? ›

Vitamin K does not cross the placenta to the developing baby, and the gut does not have any bacteria to make vitamin K before birth. After birth, there is little vitamin K in breast milk and breastfed babies can be low in vitamin K for several weeks until the normal gut bacteria start making it.

Do babies get vitamin K from breast milk? ›

No. Breast milk is low in vitamin K. Breast milk from mothers who are taking vitamin K supplements is also low in vitamin K. The American Academy of Pediatrics recommends that all newborns, whether breastfed or formula fed, receive a one-time intramuscular shot of vitamin K within 6 hours after birth.

What are the symptoms of vitamin K hemorrhage? ›

What are the symptoms of vitamin K deficiency bleeding in a newborn?
  • Blood in your baby's stool that make it black and sticky (tarry)
  • Blood in your baby's urine.
  • Oozing of blood from around your baby's umbilical cord or circumcision site.
  • Bruising more easily than normal. ...
  • Being very sleepy or fussy.

How do you stop bleeding from vitamin K? ›

Taking vitamin K by mouth or by IV can help prevent bleeding in people with VKCFD. IV products can only be given by a healthcare provider. Reversing the blood thinning effects of warfarin. Taking vitamin K1 by mouth or by IV can reverse the effects of warfarin, a blood thinner.

What is the role of vitamin K in postpartum hemorrhage? ›

Vitamin K deficiency can pose a significant health risk to both the mother and the fetus, which can cause bleeding, especially in newborns. Hemorrhage in these cases occurs due to low levels of prothrombin, which is a substance that depends upon vitamin K.

What happens if you dont give newborn vitamin K? ›

Babies are born with very small amounts of vitamin K stored in their bodies, which can lead to a serious bleeding problem known as vitamin K deficiency bleeding (VKDB). VKDB can lead to brain damage and death. Bleeding from vitamin K deficiency is a risk during the first 6 months of life.

Can lacking vitamin K cause excessive bleeding? ›

What are the symptoms of vitamin K deficiency? Not having enough vitamin K in the body makes you more likely to bleed. You may bruise more easily than usual, or it may be more difficult to stop bleeding after an injury or surgery. It can also make your periods heavier.

What does an excess of vitamin K cause in a newborn? ›

Vitamin K toxicity is extremely rare. The only reported toxicity comes from menadione, which has no use in humans. Its toxicity is thought to be associated with its water-soluble properties. When toxicity does occur, it manifests with signs of jaundice, hyperbilirubinemia, hemolytic anemia, and kernicterus in infants.

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